This week was both the best and worst in the class. We received much more information regarding our project--very helpful information that we never thought to research before talking with the two experts. However, this information maybe wasn't what we wanted to hear (unhappy face).
Dr. Donald Coen first talked to us regarding our choice of viral vector. He provided useful insight as to why EBV was good to use in theory, but it would be very difficult to introduce into the gut for a variety of issues. He told us of the possibilities of other vectors (pox viruses for example) that may be worth our time to research. After talking with Dr. Coen, we all felt as though we were back at square one--at least we had a wealth of new information to combine with our preexisting knowledge to create a perfect design.
Next, Dr. Xi He, an expert in Wnt signalling told us of the four most common mutations in the Wnt pathway that could lead to a cell turning cancerous. This will be our other focus moving forward: finding out more about the big four mutations, and trying to implement them into our system.
The next few days will be full of us attempting to make last minute adjustments to our system with the suggestions proposed by the two experts. I am confident we can get everything researched and implemented before the final presentation, and make the best system possible with the information we have thus far.
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